Cardiovascular disease research should focus more on patients’ T3 levels than TSH

Science has already shown that at T3 is more important than TSH to the functional parameters of the cardiovascular system: At the molecular and tissue level, the T3 hormone directly affects the cardiovascular system in a myriad of important ways (see "Low T3’s effects on the cardiovascular system.") Why, then, when researchers shift their focus …

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Low T3 effects on the cardiovascular system

When people think of cardiovascular symptoms and thyroid hormones, they usually think first about hyperthyroidism (EXCESS T3 thyroid hormone). However, hypothyroidism (DEFICIENT T3 thyroid hormone) has an equally powerful effect on the heart and blood vessels. It can just be slower, more long-term, and less dramatic. Did you know? Heart failure occurs in hypothyroidism. (See …

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Do you have a Reverse T3 problem?

Across Canada, Reverse T3 testing is often offered for a fee -- patients usually pay for it. It has been this way for more than a few years now. As patients (and doctors), we need to know when we can save our money and avoid testing Reverse T3 by learning about its elevation indirectly. Here's …

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Interpreting Free T3 and Free T4 in therapy

Hypothyroidism is a thyroid hormone insufficiency, so it's only logical to measure the success of therapy by the goal: T4 and T3 thyroid hormone sufficiency. Especially T3 sufficiency, the active hormone. Lab tests like Free T3 and Free T4 can indicate "relative" T3 and T4 sufficiency in bloodstream ... but one has to carefully interpret …

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HISTORY: L-T3 monotherapy in 1957

Sometimes science does not retain knowledge, but rather chooses to forget. After endocrinology fell in love with L-T4 monotherapy, it was too tempting to forget the history of the OTHER monotherapy -- L-T3 monotherapy. Modern doctors might assume that because they didn't have the TSH test back then, they were blind! They had no way …

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Give therapy options to thyroid patients

Hypothyroidism is a thyroid hormone deficiency, so it makes sense that our primary therapy involves ingesting either synthetic or animal-derived thyroid hormone. There are 2 primary forms of thyroid hormone in the human body. T4 is the relatively inactive form, with only minor non-genomic activity. It converts to T3 or to Reverse T3. T3 is …

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History of the three thyroid medications

Three thyroid hormone medications have had a long history of effective use. I discuss them in chronological order, from the earliest thyroid medication to the most recently invented. No new thyroid medications have been invented since the 1950s, although all three of them have been further refined, and various manufacturers exist for each of them. …

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