The "Choosing Wisely Canada" toolkit promoting limitation of Free T3 and Free T4 testing has been the food for some meme refutations. Choosing Wisely Canada. (n.d.). Toolkit: Less is More with T3 & T4. Retrieved December 30, 2018, from https://choosingwiselycanada.org/perspective/toolkit-t4-t3/ Recently, we've focused on their Table 2 which outlines situations they recommend NOT to order …

Continue reading MEMES: Against Table 2 in the “Choosing Wisely Canada” T3 & T4 toolkit

UBIQUITINATION: This is the "Glass ceiling" of T4 monotherapy -- there is a biological limit on how much T3 you can get out of treatment with T4 thyroid hormone alone (Synthroid, levothyroxine). The enzyme responsible for the majority of our body's T4-T3 conversion is Deiodinase Type 2 (D2), and it does its job of conversion …

Continue reading Ubiquitination: The glass ceiling of T4 monotherapy

Choosing Wisely Canada, together with the Canadian Society for Endocrinology and Metabolism, have collaborated on a harmful toolkit to reduce Free T3 and Free T4 hormone testing in order to save money. As you can see in their Table 2 from page 9 of their toolkit, they want to prevent T3 and T4 testing in …

Continue reading Our response to Choosing Wisely’s harmful Table 2

We have compiled a bibliography on Atrophic Thyroiditis and the TSHR antibody that is continually under development. 127 items exist in the bibliography as of December 2018 Screenshot The database is in a Google Spreadsheet. Click this link to access : https://docs.google.com/spreadsheets/d/1MlwMCGUnEF_ptUE9S9znMnN5oNkuAqA2fUNxvD2zrRw/edit?usp=sharing  

Why have clinical trials of T3-T4 combination therapy failed to show significant benefit? Hoermann et al explain that the trials and the meta-analyses exhibit a fundamental problem with research methodology and a fundamental misunderstanding of thyroid hormone relationships that results in statistical errors. SOURCE Hoermann, R., Midgley, J. E. M., Larisch, R., & Dietrich, J. …

Continue reading Simpson’s paradox: Hoermann et al explain why T4-T3 therapy trials are faulty

Do you know about the THIRD type of autoimmune thyroid disease? Atrophic Thyroiditis causes hypothyroidism, but it's NOT Hashimoto's. Myths and lack of knowledge Most doctors and patients have never heard about Atrophic Thyroiditis (AT). That's because it's not taught in med school, and an ultrasound is not usually ordered unless a thyroid gland is …

Continue reading The THIRD type of autoimmune thyroid disease: Atrophic Thyroiditis

The government tells us this about the process of our petition: Verification "On December 25th at 3:13 pm EDT the petition will close for signatures. Then the Clerk of Petition’s office will verify to make sure that there are 500 valid signatures. They will then send our office a printed sheet with a certification page …

Continue reading Coming soon: Jan. 28, 2019 petition reading in the House of Commons