Free T3 peaks and valleys in T3 and NDT therapy

Lack of knowledge about Free T3 peaks and valleys contributes to failure and frustration in T3-based therapies, including desiccated thyroid and T3-T4 combination therapy. On patient support groups, I often see conversations that go like this: "My FT3 result was over reference range, FT4 low in range, and my TSH was low, so my doctor … Continue reading Free T3 peaks and valleys in T3 and NDT therapy

Caution: Doctors perform T3-ectomies without our consent

We all know a "thyroidectomy" is the surgical removal of a thyroid gland. Nobody removes a vital gland without a patient's informed consent. If your medical system and doctor are ethical, you as a patient have the opportunity to weigh the risks and benefits of the procedure and give signed consent. We need to consider … Continue reading Caution: Doctors perform T3-ectomies without our consent

Principles and Practical tips for Reverse T3, FT3, FT4

This post follows up on several recent posts on the topic of Reverse T3 (RT3) and our thyroid hormone conversion enzymes, the three deiodinases. Here I'm providing some practical tips about Reverse T3 testing, test interpretation, and where we should be focusing our attention. In these posts, I aim to improve thyroid therapy by debunking … Continue reading Principles and Practical tips for Reverse T3, FT3, FT4

RT3 inhibits T4-T3 conversion. How worried should we be?

[Post updated May 2, 2021] Many thyroid patients have acquired concerns about Reverse T3 (RT3) by reading Kent Holtorf's web pages. Likely even more have learned by reading Reverse T3 information on the Stop the Thyroid Madness (STTM) thyroid patients' website, which has been influenced by Holtorf, whom they cite. On the positive side, both … Continue reading RT3 inhibits T4-T3 conversion. How worried should we be?

Deiodinase Type 3, not RT3, plays the T3-blocking role

A lot of internet myths and misinformation surrounds Reverse T3 (RT3). Well-meaning people have attributed to the hormone a “T3-blocking” function. However, the enzyme deiodinase type 3 (D3) (NOT Vitamin D3, which is very different) is the main blocker of T3 hormone. Deiodinase type 3 (D3), regulated by the DIO3 gene, is the enzyme that … Continue reading Deiodinase Type 3, not RT3, plays the T3-blocking role