What can prevent T3 from getting into thyroid receptors?

This is part 2 of a post which began with the question "How do we get enough T3 into our thyroid hormone receptors?"  In this post, I discuss the factors that can prevent T3 from getting into receptors. There are two factors that usually operate together: 1) the "variable rate" of T4 conversion in cells, … Continue reading What can prevent T3 from getting into thyroid receptors?

How do we get enough T3 into thyroid hormone receptors?

In thyroid disease and therapy, even when TSH is normalized, we can still be genuinely hypothyroid if we do not have enough T3 getting into our thyroid hormone receptors in cells throughout the body. Most people know there's two ways we get T3 into our cells' nuclei: From circulating Free T3, andFrom circulating Free T4 … Continue reading How do we get enough T3 into thyroid hormone receptors?