Age, sex and TSH-FT4-FT3 relationships: Advanced lessons

No one wants to be ageist or sexist in thyroid screening or diagnosis. But if we are blind to the way that age and sex can distort the hypothalamus-pituitary-thyroid (HPT) axis, our interpretations of thyroid hormone levels and TSH will inevitably become ageist and sexist by refusing to respect and accommodate human diversity. In a previous post, “Age bias may hide hypothyroidism under a normal TSH,” I discussed the transformations in TSH-FT4 relationships with age, focusing on adults. Then, I followed up with a post focusing on “Pediatric and teenage TSH, FT4, and FT3 levels.” Those previous posts discuss mainly …

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