Renew the paradigm. Optimize our therapy.
We've known since at least 2002 that being within "normal range" is never good enough when it comes to thyroid hormone blood tests. An important set of articles has taught us that each human being has an optimal range for TSH, Total T4 and Total T3 that is far less the width of the population-wide …
Continue reading Individual thyroid ranges are 38-68% the size of the lab reference range
What does NEW thyroid science have to say on the topic of thyroid pharmaceutical equivalency? How many micrograms of L-T3 Liothyronine (i.e. Cytomel) are equivalent to L-T4 Levothyroxine (i.e. Synthroid)? Thyroid hormone pharmaceutical monographs currently provide very rigid and low-ratio equivalency statements: ERFA Canada says "Desiccated thyroid 60 mg is usually considered equivalent to ... …
Continue reading L-T3 pharmaceutical equivalency, Part 2: New thyroid science
In thyroid therapy, how many micrograms of Cytomel (T3) are equivalent to how many micrograms of Synthroid (T4)? Equivalency statements in the product monographs for Pfizer Canada's Cytomel and for ERFA Canada's "Thyroid" (NDT brand) claim that a 25 mcg dose of Liothyronine sodium (L-T3) is "considered equivalent" to 100 mcg / μg (0.1 mg) …
Continue reading No, 25 mcg of L-T3 Liothyronine isn’t equivalent to 100 mcg L-T4
Part 1: Five historical voices say: "No, 25 mcg of L-T3 Liothyronine isn’t equivalent to 100 mcg L-T4" Part 2: Contemporary thyroid science: "L-T3 pharmaceutical equivalency, Part 2: New thyroid science" REFERENCES Pharmaceutical monographs Armour Thyroid web page: https://www.rxlist.com/armour-thyroid-drug.htm#description Erfa Thyroid monograph, page 8 https://pdf.hres.ca/dpd_pm/00034857.PDF Pfizer Cytomel monograph, page 12 https://www.pfizer.ca/sites/default/files/201710/Cytomel_PM.pdf Mylan Synthroid monograph, page …
Robert Utiger, M.D. (1931-2008) is well known in endocrinology as the father of the TSH test. Despite his trust in the TSH test, in his publications he acknowledged that TSH behaved very unnaturally in response to T3 levels in blood while dosing T3 thyroid medication. What Utiger discovered in the 1970s and 1980s about the …
Continue reading A Dialogue with Utiger: T3-based thyroid therapy over-suppresses TSH
Our new name is "Thyroid Patients Canada." We're on the path to becoming a registered federal non-profit charitable organization. Our website will still be Thyroidpatients.ca. I will be updating our materials to reflect our new name. This is exciting! I'll share other milestones as we go through the process. If you'd like to help our …
In standard T4 thyroid therapy, TSH normalization is so easy to achieve that it is almost impossible to fail. First, TSH out of range is the judge of an initial DIAGNOSIS. Next, normal TSH becomes the sole TARGET of therapy. Finally, normal TSH becomes the sole JUDGE of therapy success. This is faulty reasoning. There …
