No, 25 mcg of L-T3 Liothyronine isn’t equivalent to 100 mcg L-T4

In thyroid therapy, how many micrograms of Cytomel (T3) are equivalent to how many micrograms of Synthroid (T4)? Equivalency statements in the product monographs for Pfizer Canada's Cytomel and for ERFA Canada's "Thyroid" (NDT brand) claim that a 25 mcg dose of Liothyronine sodium (L-T3) is "considered equivalent" to 100 mcg / μg (0.1 mg) …

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L-T3 and L-T4 Equivalency: Reference List

Part 1: Five historical voices say: "No, 25 mcg of L-T3 Liothyronine isn’t equivalent to 100 mcg L-T4" Part 2: Contemporary thyroid science: Post coming soon. REFERENCES Pharmaceutical monographs Armour Thyroid web page: https://www.rxlist.com/armour-thyroid-drug.htm#description Erfa Thyroid monograph, page 8 https://pdf.hres.ca/dpd_pm/00034857.PDF Pfizer Cytomel monograph, page 12 https://www.pfizer.ca/sites/default/files/201710/Cytomel_PM.pdf Mylan Synthroid monograph, page 25 https://www.mylan.ca/-/media/mylanca/documents/english/product%20pdf/1.3.1-synthroid-pm.pdf Thyroid scientific literature …

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A Dialogue with Utiger: T3-based thyroid therapy over-suppresses TSH

Robert Utiger, M.D. (1931-2008) is well known in endocrinology as the father of the TSH test. Despite his trust in the TSH test, in his publications he acknowledged that TSH behaved very unnaturally in response to T3 levels in blood while dosing T3 thyroid medication. What Utiger discovered in the 1970s and 1980s about the …

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Our new name: Thyroid Patients Canada

Our new name is "Thyroid Patients Canada." We're on the path to becoming a registered federal non-profit charitable organization. Our website will still be Thyroidpatients.ca. I will be updating our materials to reflect our new name. This is exciting! I'll share other milestones as we go through the process. If you'd like to help our …

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Overreliance on TSH is a thyroid therapy policy that fails to detect its own failure

In standard T4 thyroid therapy, TSH normalization is so easy to achieve that it is almost impossible to fail. First, TSH out of range is the judge of an initial DIAGNOSIS. Next, normal TSH becomes the sole TARGET of therapy. Finally, normal TSH becomes the sole JUDGE of therapy success. This is faulty reasoning. There …

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Targeting TSH? It’s not as specific or as sensitive as people claim.

Patients and doctors are often told there's an ideal "target" for TSH levels. Some believe that in thyroid therapy, your TSH should be below the upper reference limit, some say it should be below 2.5, and a minority will even say it should be suppressed entirely whether or not you are a thyroid cancer patient. …

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Flexible-Ratio T3, T4, and NDT Combination Thyroid Therapy

Here I bring thyroid science into a discussion of effectively adapting and managing the most flexible form of thyroid therapy, T4-T3 combination therapy. This is a model capable of adapting to an individual's unique thyroid disability and response to thyroid medication. Finding an individual's optimal combination therapy is medically necessary when T4 monotherapy fails due …

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