Renew the paradigm. Optimize our therapy.
No one wants to be ageist or sexist in thyroid screening or diagnosis. But if we are blind to the way that age and sex can distort the hypothalamus-pituitary-thyroid (HPT) axis, our interpretations of thyroid hormone levels and TSH will inevitably become ageist and sexist by refusing to respect and…
Scientists that study the effect of age on thyroid-stimulating hormone (TSH), Free T4 (FT4) and Free T3 (FT3) thyroid hormones often exclude the age group from birth up to age 16, 18, or 19. They usually exclude children and teenagers because they know they are different. Describing their TSH and…
Scientists have been explaining that TSH responds to thyroid hormones differently in childhood, early adulthood, late adulthood and very advanced age. This poses a problem for regions that have implemented TSH-only screening for thyroid dysfunction. The effect of age on TSH is one of many factors that can make this…
If you are well-informed by current thyroid science, you already know the answer to the question in the title. “No. A normal TSH cannot rule out thyroid disease.” Since the 1990s, physicians have been taught to use simplistic category-based interpretations of TSH (and Free T4) as “in or out of…
A Google search for “thyroid function tests” brought up a definition square at the top of the search results. It says that “Thyroid function tests” is a collective term for blood tests used to check the function of the thyroid. A TFT panel typically includes thyroid-stimulating hormone (TSH, thyrotropin) and thyroxine (T4), and triiodothyronine (T3) depending on…