Author Archives
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Q&A. Dosing T3 in light of circadian rhythm
Question In response to my post The Significance of the TSH-T3 Circadian Rhythm, Julien wrote: “Thank you for such an informative article. If I interpreted this correctly, for the hypothyroid patients on combined T3+T4 therapy, it would seem that taking… Read More ›
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The significance of the TSH-FT3 circadian rhythm
In my earlier post about circadian rhythms in thyroid health, I asked two quiz questions about TSH, FT3 and FT4 variability. First I asked “Which value varies the most during the day, a) TSH, b) Free T3 or c) Free… Read More ›
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Circadian rhythms of TSH, Free T4 and Free T3 in thyroid health
Let’s take a thyroid hormone rhythm quiz to get into this article. It’s only two questions long, and both questions and answers are in this introduction. Question #1. Which value varies the most during the day, a) TSH, b) Free… Read More ›
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Infographic: Thyroid hormone journey
This summary blog post will take you through a visual journey as you follow thyroid hormones through bloodstream, transporters, cells, and receptors. This infographic is not like most others you’ll see that portray a gland-centric view of the HPT axis…. Read More ›
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Visual bias: The pituitary gland in HPT axis diagrams
Too many diagrams focus on the “HPT axis,” in which the Hypothalamus, the Pituitary, and Thyroid gland are the biggest icons. Take for example this diagram from Ortiga-Carvalho’s chapter in a physiology textbook. The huge, super-ballsy pituitary. Seriously? In diagrams… Read More ›
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Tissue RNA expression of DIO1, DIO2, and DIO3
No, this is not just an article for thyroid science buffs. Anyone who claims to understand thyroid hormone metabolism should become comfortable using the word “deiodinase.” It’s just as important a word for thyroid disease as “insulin” is for diabetes…. Read More ›
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LT3 monotherapy withdrawal: Clearance and effects
How long does it take for the final dose of synthetic LT3 (Liothyronine) hormone to clear from blood, and how much suffering might a withdrawal cause? This is an important question for many people who dose LT3. They want to… Read More ›
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Acella NP Thyroid recall: maternal risk inflated
Acella, the makers of NP Thyroid, issued a voluntary recall notice on May 22, 2020. This is part 2 of a two-part series reviewing the drug recall notice’s statements and the science behind them. [Part 1: Acella NP Thyroid recall:… Read More ›