Diagnostic concepts like “subclinical hypothyroidism” have become cognitive barriers to understanding the adaptations and dysfunctions of the aging hypothalamus-pituitary-thyroid (HPT) axis. Thyroid diagnostic categories are usually based on whether TSH and FT4 are in range, above range, or below range,… Read More ›
Scientists have been explaining that TSH responds to thyroid hormones differently in childhood, early adulthood, late adulthood and very advanced age. This poses a problem for regions that have implemented TSH-only screening for thyroid dysfunction. The effect of age on… Read More ›
Too many diagrams focus on the “HPT axis,” in which the Hypothalamus, the Pituitary, and Thyroid gland are the biggest icons. Take for example this diagram from Ortiga-Carvalho’s chapter in a physiology textbook. The huge, super-ballsy pituitary. Seriously? In diagrams… Read More ›
You’ve just come to your doctor for your annual check-up. Either you feel fine and you want to get a renewal of your current thyroid prescription, or you feel rather hypothyroid and you’re hoping to get an increased dose. But… Read More ›
Does the statistically-defined “normal” TSH reference range for the healthy population describe the TSH range for a healthy individual? Does having a TSH within the normal laboratory range always mean you, as an individual are biologically euthyroid? Does falling outside… Read More ›
In a series of posts, I’m sharing my plainer-English paraphrase of a very important article in thyroid science. My hope is that the public, doctors, and educated thyroid patients can better understand and appreciate its insights. This article by Dr…. Read More ›
There’s a deep lie behind today’s TSH-based definition of “euthyroid” status and today’s policies of TSH normalization in therapy. The lie is that the loss of the thyroid and the initiation of thyroid hormone dosing has NOT altered and skewed… Read More ›
We’ve known since at least 2002 that being within “normal range” is never good enough when it comes to thyroid hormone blood tests. An important set of four articles has taught us that each human being has an optimal range… Read More ›