When we think of the many challenges Ukrainians are facing with courage today, we should remember that they lived through Chernobyl, and that they are a people living with thyroid diseases. Partly because of the Chernobyl nuclear meltdown disaster in… Read More ›
Scientific research analysis
TBAb hypothyroidism diagnosed in a mother and baby
In this post, I’d like to share with you a real-life story, suitable for the holiday season, that might warm your hearts as much as it warmed mine. And by the end, it might even motivate you to learn more… Read More ›
A complete pathway map of T4 and T3 metabolism and clearance
Biochemical pathway maps are an important aspect of medical education and medical problem-solving. They help us to view a network or series of chemical reactions in cells. In this article, I present a comprehensive science-based pathway map showing all the… Read More ›
Finkler, 1959: Liothyronine as a replacement for thyroid therapy
One of Thyroid Patients Canada’s values is to bring to light little-known aspects of the history of thyroid therapy so that it can open minds about future possibilities. The history of L-T3 (Liothyronine) monotherapy brings to light the flexibility and… Read More ›
Ingbar and Braverman’s historic study of LT4 monotherapy
As part of my post on “The thyroid gland is a T3 shield,” I reviewed a research article by Ingbar and team from 1982. Wow. What a treasure. The title of this article is “Elevated serum thyroxine concentration in patients… Read More ›
Prevalence rates for 10 chronic disorders at various FT4, TSH and FT3 levels
Which FT3, FT4 and TSH levels have the highest and lowest prevalence rates for 10 common health disorders? Hypertension Hyperlipidemia (high cholesterol) Depression Diabetes Coronary artery disease Heart failure Atrial fibrillation Peripheral vascular disease Renal failure (kidney failure) Dementia Is… Read More ›
Mimicry: The idol of T3-T4 combo therapy 2004-2014
They say that history is written by the victors. Not always. Sometimes histories are written by advocates for the oppressed and disenfranchised. A common theme on our website is the need to see current practices and thyroid therapy challenges in… Read More ›
The foundations of synthetic T3-T4 therapy in the 1990s
A trend in thyroid therapy, sparked by a 1995 rat study, attempted to mimic a narrowly estimated T3:T4 ratio secreted by human thyroid glands. This trend was based on a theory of pharmaceutical mimicry of “the” thyroid gland. Its proponents… Read More ›