Diagnostic concepts like “subclinical hypothyroidism” have become cognitive barriers to understanding the adaptations and dysfunctions of the aging hypothalamus-pituitary-thyroid (HPT) axis. Thyroid diagnostic categories are usually based on whether TSH and FT4 are in range, above range, or below range,… Read More ›
No one wants to be ageist or sexist in thyroid screening or diagnosis. But if we are blind to the way that age and sex can distort the hypothalamus-pituitary-thyroid (HPT) axis, our interpretations of thyroid hormone levels and TSH will… Read More ›
Scientists have been explaining that TSH responds to thyroid hormones differently in childhood, early adulthood, late adulthood and very advanced age. This poses a problem for regions that have implemented TSH-only screening for thyroid dysfunction. The effect of age on… Read More ›