The Spectrum of Thyroid Autoimmunity

Let's get to know what many of us thyroid patients have in common, and what makes each of us unique. Are you an autoimmune thyroid disease (AITD) patient? If so, what kind of autoimmune thyroid disease do you have? How do you know for sure? I ask this final question because very few of us … Continue reading The Spectrum of Thyroid Autoimmunity

TSHR Antibodies can distort TSH secretion

There’s an underestimated, under-studied TSH feedback loop that almost nobody talks about: The ultrashort feedback loop at the pituitary gland. By means of acting on this feedback loop, a thyroid antibody may have a direct effect on TSH secretion as well as our T4 and T3 levels. This antibody is far more prevalent and clinically … Continue reading TSHR Antibodies can distort TSH secretion

When is Low TSH not hyperthyroidism?

Q: When is a low TSH not hyperthyroidism? The answer is huge -- in central hypothyroidism, in low T3 syndrome, in the first trimester of pregnancy... AND in cases where thyroid therapy achieves euthyroid status without causing tissue thyrotoxicosis. In many posts on this blog, we've detailed the reasons why TSH is a poor indicator … Continue reading When is Low TSH not hyperthyroidism?