The loss of thyroid clinical knowledge from Werner & Ingbar’s The Thyroid

Decades ago, a lot more doctors knew how thyroid hormone levels influenced all organs and tissues’ health. It wasn’t all about the influence of thyroid hormones on the TSH. It was more about the influence of truly adequate thyroid hormone levels on real health outcomes. A lot more doctors learned and understood that if thyroid …

Continue reading The loss of thyroid clinical knowledge from Werner & Ingbar’s The Thyroid

Pregnancy thyrotoxicosis vs just a low TSH due to HCG hormone

Table 17.1 in Braverman & Cooper's 2013 chapter in Werner & Ingbar's The Thyroid textbook, 10th edition, lists many causes of thyrotoxicosis. One of the interesting causes of thyrotoxicosis, rarely mentioned in public discourse, is "Circulating HCG or Mutant TSHR [TSH receptor] hypersensitive to HCG." What is HCG? "Human chorionic gonadotropin" is a hormone produced …

Continue reading Pregnancy thyrotoxicosis vs just a low TSH due to HCG hormone

Thyrotoxicosis can occur with high or normal TSH?

Table 17.1 in Braverman & Cooper's 2013 chapter in Werner & Ingbar's The Thyroid textbook, 10th edition, lists many causes of thyrotoxicosis. The only time the TSH _hormone_ is listed as a cause of thyrotoxicosis is in the case of "Inappropriate TSH hypersecretion." If thyrotoxicosis can occur when TSH is inappropriately _high_ or non-suppressed in …

Continue reading Thyrotoxicosis can occur with high or normal TSH?

Thyrotoxicosis vs. Low TSH

Our medical system has invested so much in the TSH test that we've given it authority to override medical discernment about thyrotoxicosis. The oft-repeated mantras that "TSH is the most sensitive and specific test" and "the only necessary test" have blinded many doctors to the diverse influences that can suppress or inflate TSH secretion. Unscientific …

Continue reading Thyrotoxicosis vs. Low TSH

Thyrotoxicosis? Many factors can lower TSH

Many substances and health factors can, independently of thyroid hormones, lower TSH secretion significantly. These factors are not listed in Braverman & Cooper's chapter on thyrotoxicosis in Werner & Ingbar's The Thyroid textbook, 10th edition 2013, because their chapter avoids defining the syndrome by a low TSH. Nevertheless, these TSH-lowering factors should always be mentioned …

Continue reading Thyrotoxicosis? Many factors can lower TSH

Thyrotoxicosis: Symptoms and signs

Much confusion exists about the value of symptoms and signs in the diagnosis of thyrotoxicosis. The most common view is to dismiss symptoms entirely because each, considered separately, is "nonspecific" to thyrotoxicosis. However, there is no such thing as a "thyroid-specific" symptom because thyroid hormones have their effects in every organ and system of the body.  What's …

Continue reading Thyrotoxicosis: Symptoms and signs

References for Thyrotoxicosis vs. Low TSH series

Posts in this series July 2019 Thyrotoxicosis? Many factors can lower TSH Thyrotoxicosis: Symptoms and signs Thyrotoxicosis vs. Low TSH Thyrotoxicosis can occur with high or normal TSH? TSH "can be very misleading" during thyroid therapy, say researchers How TSH ultrashort feedback works, and antibody interference Pregnancy thyrotoxicosis vs just a low TSH due to …

Continue reading References for Thyrotoxicosis vs. Low TSH series