Category: Tissue hypothyroidism

Prevalence rates for 10 chronic disorders at various FT4, TSH and FT3 levels

by thyroidpatientsca, posted in Cardiovascular, Chronic diseases, Health conditions, Low T3 Syndrome / NTIS, Research Reviews, Thyrotoxicosis, Tissue hypothyroidism

Which FT3, FT4 and TSH levels have the highest and lowest prevalence rates for 10 common health disorders? Hypertension Hyperlipidemia (high cholesterol) DepressionDiabetesCoronary artery diseaseHeart failureAtrial fibrillationPeripheral vascular diseaseRenal failure (kidney failure)Dementia Is high-normal TSH and low FT3 associated with one condition, while high-normal FT4 and low or high TSH strongly associated with another condition? … Continue reading Prevalence rates for 10 chronic disorders at various FT4, TSH and FT3 levels

What can prevent T3 from getting into thyroid receptors?

by thyroidpatientsca, posted in T3 hormone, Tissue hypothyroidism

This is part 2 of a post which began with the question "How do we get enough T3 into our thyroid hormone receptors?"  In this post, I discuss the factors that can prevent T3 from getting into receptors. There are two factors that usually operate together: 1) the "variable rate" of T4 conversion in cells, … Continue reading What can prevent T3 from getting into thyroid receptors?

How do we get enough T3 into thyroid hormone receptors?

by thyroidpatientsca, posted in T3 hormone, T3 sufficiency, Tissue hypothyroidism

In thyroid disease and therapy, even when TSH is normalized, we can still be genuinely hypothyroid if we do not have enough T3 getting into our thyroid hormone receptors in cells throughout the body. Most people know there's two ways we get T3 into our cells' nuclei: From circulating Free T3, andFrom circulating Free T4 … Continue reading How do we get enough T3 into thyroid hormone receptors?

Visualizing thyroid hormone activity in cells: T3 and RT3 in context

by thyroidpatientsca, posted in Deiodinase Type 2, Deiodinase Type 3, Deiodinases, Research Reviews, RT3 - Reverse T3, T3 hormone, T3 sufficiency, TH Receptors, Tissue hypothyroidism, Transporters

I've recently been inspired by an visual of thyroid hormone cellular action published by Bianco and colleagues in September, 2019. This visual has taught me a new way of seeing these hormones' pathways of movement and activity in our bodies. I've read Bianco's article quite thoroughly in light of the image, and as a result … Continue reading Visualizing thyroid hormone activity in cells: T3 and RT3 in context

The basics of thyroid hormone action, transport and conversion

by thyroidpatientsca, posted in Deiodinase Type 2, Deiodinase Type 3, Deiodinases, Healthy thyroid axis, RT3 - Reverse T3, T2 hormone, T3 hormone, T3 sufficiency, T4 hormone, TH Receptors, Tissue hypothyroidism, Transporters

This comprehensive educational post collects the basics of thyroid hormone, transport and conversion. T3 action on nuclear receptors Every organ and tissue in your body must maintain a healthy level of T3 hormone activity to function properly. Bloodstream T3 supply and local T3 action powerfully influences how every organ operates, from our liver to our … Continue reading The basics of thyroid hormone action, transport and conversion