RT3 inhibits T4-T3 conversion. How worried should we be?

Many thyroid patients have learned to fear Reverse T3 (RT3) by reading Kent Holtorf's web pages. Likely even more have learned by reading Reverse T3 information on the Stop the Thyroid Madness (STTM) thyroid patients' website, which has been influenced by Holtorf, whom they cite. On the positive side, both of these websites share a …

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Deiodinase Type 3 plays the T3-blocking role

This is part 2 of a 2-part post (It was long, so I've decided to break it into two parts). Images & principles were shared in yesterday's post: Visualizing thyroid hormone activity in cells: T3 and RT3 in context Here's the corrected & clarified image that I developed based on Bianco et al, 2019's model: …

Continue reading Deiodinase Type 3 plays the T3-blocking role

Visualizing thyroid hormone activity in cells: T3 and RT3 in context

I've recently been inspired by an visual of thyroid hormone cellular action published by Bianco and colleagues in September, 2019. This visual has taught me a new way of seeing these hormones' pathways of movement and activity in our bodies. I've read Bianco's article quite thoroughly in light of the image, and as a result …

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The basics of thyroid hormone action, transport and conversion

This comprehensive educational post collects the basics of thyroid hormone, transport and conversion. T3 action on nuclear receptors Every organ and tissue in your body must maintain a healthy level of T3 hormone activity to function properly. Bloodstream T3 supply and local T3 action powerfully influences how every organ operates, from our liver to our …

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Do you have a Reverse T3 problem?

Across Canada, Reverse T3 testing is often offered for a fee -- patients usually pay for it. It has been this way for more than a few years now. As patients (and doctors), we need to know when we can save our money and avoid testing Reverse T3 by learning about its elevation indirectly. Here's …

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Deiodinase type 3 and Reverse T3

The Three Deiodinases Every person has three deiodinases responsible for thyroid hormone conversion. Dear thyroid patients: if you've never heard about the deiodinases, your life and future health may depend on you learning. They can either work with your thyroid meds or against them. It's a lifelong condition, being on thyroid therapy, so there's time …

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How the three deiodinases regulate T3

Dear thyroid patients: If you've never heard about the deiodinases, your life and future health may depend on you learning about them. The deiodinases can either work with your thyroid meds or against them. It's a lifelong condition, being on thyroid therapy, so there's time for thyroid knowledge to sink in. I don't have a bioscience …

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