The loss of thyroid clinical knowledge from Werner & Ingbar’s The Thyroid

Decades ago, a lot more doctors knew how thyroid hormone levels influenced all organs and tissues’ health. It wasn’t all about the influence of thyroid hormones on the TSH. It was more about the influence of truly adequate thyroid hormone levels on real health outcomes. A lot more doctors learned and understood that if thyroid …

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Low T3 syndrome in thyroid therapy: THREE studies

In contrast with a long list of over 70 medical research articles on low T3 syndrome that excluded thyroid patients, I have only found three (3) studies so far that included patients being treated for hypothyroidism. I'll reveal their treasures and disappointments in reverse date order: Somppi, 2017 Tevaarwerk, 2014 Wadwekar, 2004 Here's how many …

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Thyroid patients are routinely excluded from low T3 syndrome (NTIS) research

Most studies of Low T3 syndrome (NTIS) routinely EXCLUDE thyroid patients. Sadly, our exclusion has become a research tradition. In this post, I lay out the landscape and extent of our exclusion from this valuable area of thyroid hormone health research. Everyone loses by our exclusion. Especially thyroid patients. Everyone has something to gain from …

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Ataoglu: Low T3 in critical illness is deadly, and adding high T4 is worse.

In 2018, Ataoglu and colleagues confirmed and expanded our knowledge of "Low T3 syndrome." Despite a normalized TSH, a Low T3 is deadly not only in acute, critical illness, but in "chronic disease." To be specific, Low T3 is more deadly in some health conditions than others. What should be really shocking to many is …

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The impact of thyroid hormone dysfunction on ischemic heart disease, and how T3 therapy may help

Finally! In the past, the overemphasis on hyperthyroidism and thyrotoxicosis and heart diseases has made many doctors think that only excess T3 and T4 is bad for the heart. We finally have an article that focuses on the real cause-effect relationships on the opposite end of the thyroid dysfunction spectrum: HYPOthyroidism. This May 2019 article …

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Low-normal FT3 increases Alzheimer’s Disease risk

SOURCE Quinlan, P., Horvath, A., Wallin, A., & Svensson, J. (2019). Low serum concentration of free triiodothyronine (FT3) is associated with increased risk of Alzheimer’s disease. Psychoneuroendocrinology, 99, 112–119. https://doi.org/10.1016/j.psyneuen.2018.09.002  JAN 2019: Study reports increased risk of Alzheimer's disease with low-normal Free T3 thyroid hormone. "Patients in the lowest FT3 quartile had a more than …

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Review: Chronic fatigue syndrome and Low T3

Ruiz-Núñez et al's 2018 article, "Higher Prevalence of “Low T3 Syndrome in Patients With Chronic Fatigue Syndrome," breaks down the common misconception that Low T3 syndrome only occurs in critical illness. Low T3 can also occur in a chronic state during chronic illness. A more extreme state of free T3 below reference range occurred in …

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