No, 25 mcg of L-T3 Liothyronine isn’t equivalent to 100 mcg L-T4

In thyroid therapy, how many micrograms of Cytomel (T3) are equivalent to how many micrograms of Synthroid (T4)? Equivalency statements in the product monographs for Pfizer Canada's Cytomel and for ERFA Canada's "Thyroid" (NDT brand) claim that a 25 mcg dose of Liothyronine sodium (L-T3) is "considered equivalent" to 100 mcg / μg (0.1 mg) …

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L-T3 and L-T4 Equivalency: Reference List

Part 1: Five historical voices say: "No, 25 mcg of L-T3 Liothyronine isn’t equivalent to 100 mcg L-T4" Part 2: Contemporary thyroid science: Post coming soon. REFERENCES Pharmaceutical monographs Armour Thyroid web page: https://www.rxlist.com/armour-thyroid-drug.htm#description Erfa Thyroid monograph, page 8 https://pdf.hres.ca/dpd_pm/00034857.PDF Pfizer Cytomel monograph, page 12 https://www.pfizer.ca/sites/default/files/201710/Cytomel_PM.pdf Mylan Synthroid monograph, page 25 https://www.mylan.ca/-/media/mylanca/documents/english/product%20pdf/1.3.1-synthroid-pm.pdf Thyroid scientific literature …

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Flexible-Ratio T3, T4, and NDT Combination Thyroid Therapy

Here I bring thyroid science into a discussion of effectively adapting and managing the most flexible form of thyroid therapy, T4-T3 combination therapy. This is a model capable of adapting to an individual's unique thyroid disability and response to thyroid medication. Finding an individual's optimal combination therapy is medically necessary when T4 monotherapy fails due …

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The mini-T3-mono-combination therapy model vs NDT and others

I'd like to talk about contemporary researchers' more rigid and limited approach to combination therapy. This is the model whose many limitations I point out with the ridiculously long label "mini-T3-mono-combination" therapy. I'll go over some of the history behind this model, the source of the rigid ratios that we learned about in our series …

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Want to help? Join a Thyroid Patients Campaign Working Group

Let's get to work together! How? It's easy to do on Facebook. Not on Facebook? Currently we're only set up for group interaction on Facebook, sorry. That's where we were "born" and where we are most active. But please don't run away! If you can't or won't join Facebook but still want to help using …

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Low T3 syndrome in thyroid therapy: THREE studies

In contrast with a long list of over 70 medical research articles on low T3 syndrome that excluded thyroid patients, I have only found three (3) studies so far that included patients being treated for hypothyroidism. I'll reveal their treasures and disappointments in reverse date order: Somppi, 2017 Tevaarwerk, 2014 Wadwekar, 2004 Here's how many …

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Thyroid therapies: What my life is like in the T3-monotherapy wheelchair

Here, I'll use my own personal example to discuss a few dimensions of T3 monotherapy, which I envision as a "wheelchair." I'm drawing on the fictional analogy I developed in an earlier post, where I imagined thyroid disease like crippling foot disease. The therapy of 100% T4 can be seen like a walking stick or …

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