There’s an underestimated, under-studied TSH feedback loop that almost nobody talks about: The ultrashort feedback loop at the pituitary gland. By means of acting on this feedback loop, a thyroid antibody may have a direct effect on TSH secretion as well as our T4 and T3 levels. This antibody is far more prevalent and clinically … Continue reading TSHR Antibodies can distort TSH secretion
Category: Pituitary gland
The pituitary response is abnormal. Stop TSH worship.
After oversimplifying T4 conversion as if it only converts into T3 (see Part 1 of this post), Canada's endocrinology association make the claim that: "Intracellular T3 levels regulate pituitary secretion and blood levels of TSH, as well as the effects of thyroid hormone in multiple organs." (1) This may be partially true, but it is … Continue reading The pituitary response is abnormal. Stop TSH worship.