One of Thyroid Patients Canada’s values is to bring to light little-known aspects of the history of thyroid therapy so that it can open minds about future possibilities. The history of L-T3 (Liothyronine) monotherapy brings to light the flexibility and… Read More ›
Thyroid therapy
Ingbar and Braverman’s historic study of LT4 monotherapy
As part of my post on “The thyroid gland is a T3 shield,” I reviewed a research article by Ingbar and team from 1982. Wow. What a treasure. The title of this article is “Elevated serum thyroxine concentration in patients… Read More ›
Gullo: LT4 monotherapy and thyroid loss invert FT3 and FT4 per unit of TSH
In 2011, Gullo’s research team published a landmark study in thyroid therapy titled “Levothyroxine Monotherapy Cannot Guarantee Euthyroidism in All Athyreotic Patients.” Gullo and colleagues examined the TSH, FT3 and FT4 levels and the FT3:FT4 ratios of 1,811 thyroidless patients… Read More ›
Mimicry: The idol of T3-T4 combo therapy 2004-2014
They say that history is written by the victors. Not always. Sometimes histories are written by advocates for the oppressed and disenfranchised. A common theme on our website is the need to see current practices and thyroid therapy challenges in… Read More ›
The foundations of synthetic T3-T4 therapy in the 1990s
A trend in thyroid therapy, sparked by a 1995 rat study, attempted to mimic a narrowly estimated T3:T4 ratio secreted by human thyroid glands. This trend was based on a theory of pharmaceutical mimicry of “the” thyroid gland. Its proponents… Read More ›
RLC Labs issues Nature-Throid and WP-thyroid recall for subpotency
Oh my. Now another American desiccated thyroid (NDT) brand recall? Earlier this year, Acella’s NP thyroid was found to be superpotent (over 110% on the T3 content), and they issued a voluntary recall. Now, as of August 25, 2020, Nature-Throid… Read More ›
Q&A. Dosing T3 in light of circadian rhythm
[Post updated Aug 5, 2020 with additional sample images.] Question In response to my post The Significance of the TSH-T3 Circadian Rhythm, Julien wrote: “Thank you for such an informative article. If I interpreted this correctly, for the hypothyroid patients… Read More ›
LT3 monotherapy withdrawal: Clearance and effects
How long does it take for the final dose of synthetic LT3 (Liothyronine) hormone to clear from blood, and how much suffering might a withdrawal cause? This is an important question for many people who dose LT3. They want to… Read More ›