T3-T4 combo-therapy
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How to calculate LT3 vs. LT4 substitution: New thyroid science
What does NEW thyroid science have to say on the topic of thyroid pharmaceutical equivalency? How many micrograms of L-T3 Liothyronine (i.e. Cytomel) are equivalent to L-T4 Levothyroxine (i.e. Synthroid)? Thyroid hormone pharmaceutical monographs currently provide very rigid and low-ratio equivalency statements: In my previous post, I uncovered the historical origins of this low 25:100…
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How to calculate LT3 vs. LT4 substitution: History had it right
During therapy for hypothyroidism, dose adjustments may include changing thyroid hormone pharmaceuticals or combining them in a certain ratio. To prevent overdose or underdose at the new total dosage, a physician will need to estimate the substitution, and later adjust the dose to the individual’s response. The initial calculation needs to be physiologically accurate. Is…
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Flexible-Ratio T3, T4, and NDT Combination Thyroid Therapy
Here I bring thyroid science into a discussion of effectively adapting and managing the most flexible form of thyroid therapy, T4-T3 combination therapy. This is a model capable of adapting to an individual’s unique thyroid disability and response to thyroid medication. Finding an individual’s optimal combination therapy is medically necessary when conventional T4 monotherapy fails…
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The mini-T3-mono-combination therapy model vs NDT and others
I’d like to talk about contemporary researchers’ rigid and limited approach to combination therapy. This is the model whose many limitations I point out with the ridiculously long label “mini-T3-mono-combination” therapy. I’ll go over some of the history behind this model, the source of the rigid ratios that we learned about in our series on…
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Question Pilo’s 1990 study. It can be misused to limit your T3 supply.
In this series, I am examining two T4-T3 thyroid hormone ratios that have been circulating in thyroid medical literature for decades. The first ratio is the “molar ratio” of T4 and T3 hormone secretion from the thyroid gland. The second ratio is the theory that the human body derives 20% of its T3 hormone supply from…