Thyroid pharma
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Trials of T3, desiccated thyroid and thyroxine in 1958
Here’s my review of this treasure, an article about T3 therapy from the scientific literature in the 1950s… TITLE: “TRIIODOTHYRONINE—Clinical Effects in Patients with Suboptimal Response to Other Thyroid Preparations” — LINK: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1512399/ In this article, “Thirty patients with evidence of hypometabolism or a clinically related condition were given triiodothyronine after suboptimal response to thyroxin or…
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You can’t get T3 from muffins
Canada, Defend access to T3-hormone thyroid medications that have been approved by Health Canada and have been used in therapy for decades. Drug shortages and cost-cutting guidelines are preventing good doctors from giving T3 hormone to fix chronic suboptimal T3. Let’s keep hypothyroid patients as healthy as they can be, for the cost of a…
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HISTORY: L-T3 monotherapy in 1957
Sometimes science does not retain knowledge, but rather chooses to forget. After endocrinology fell in love with L-T4 monotherapy, it was too tempting to forget the history of the OTHER monotherapy — L-T3 monotherapy. Modern doctors might assume that because they didn’t have the TSH test back then, they were blind! They had no way…
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Give therapy options to thyroid patients
Hypothyroidism is a thyroid hormone deficiency, so it makes sense that our primary therapy involves ingesting either synthetic or animal-derived thyroid hormone. There are 2 primary forms of thyroid hormone in the human body. T4 is the relatively inactive form, with only minor non-genomic activity. It converts to T3 or to Reverse T3. T3 is…
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History of the three thyroid medications
Three thyroid hormone medications have had a long history of effective use. I discuss them in chronological order, from the earliest thyroid medication to the most recently invented. No new thyroid medications have been invented since the 1950s, although all three of them have been further refined, and various manufacturers exist for each of them.…