Biochemical pathway maps are an important aspect of medical education and medical problem-solving. They help us to view a network or series of chemical reactions in cells. In this article, I present a comprehensive science-based pathway map showing all the major pathways of both T4 and T3 hormone metabolism, also including their urinary clearance. I … Continue reading A complete pathway map of T4 and T3 metabolism and clearance
Thyroid hormone metabolism is a very complicated system. A visual analogy sometimes goes a long way to assist comprehension. Throughout the body, there are at least six major pathways for T4 transformation or excretion, and at least six major pathways for T3 transformation or excretion. In the visual, the fluid represents circulating thyroid hormone concentrations. … Continue reading The leaky buckets analogy of thyroid hormone metabolism
Surprise! You get a little bonus of Triac if you dose NDT or T3, and you might want to tell your doctor about its benefits & side effects. Triac is a naturally-occurring thyroid hormone metabolite that powerfully suppresses TSH without causing thyrotoxicosis. Most doctors are unaware of it. Triac's full chemical name is "3,3′,5-triiodothyroacetic acid," … Continue reading When dosing T3, you get higher levels of Triac
