This final section of my paraphrase of Hoermann et al's landmark 2016 article articulates the shift from the limited, older TSH-T4 paradigm to the new paradigm that includes T3 hormone. Interrelational Measures and Emerging New Concepts of Thyroid Homeostasis [Paraphrase begins] TSH can play a useful role in screening patients who do not have any … Continue reading Relational Stability, part 4: The new thyroid paradigm
Category: Research Reviews
Relational Stability, part 3: Shifting TSH-T4-T3 relationships
Why are some people extremely hypothyroid while their TSH is above reference range, while others have no symptoms and are completely healthy? How important is the Free T3 test when diagnosing true "euthyroid" status within the TSH reference range? Is it true that a normal TSH alone, or a normal TSH and normal FT4 test … Continue reading Relational Stability, part 3: Shifting TSH-T4-T3 relationships
Relational Stability, Part 2: Normality of TSH and thyroid hormones
Does the statistically-defined "normal" TSH reference range for the healthy population describe the TSH range for a healthy individual? Does having a TSH within the normal laboratory range always mean you, as an individual are biologically euthyroid? Does falling outside statistical TSH normality really mean that you are hypothyroid or thyrotoxic? This is part 2 … Continue reading Relational Stability, Part 2: Normality of TSH and thyroid hormones
Relational stability among thyroid hormones and TSH, part 1
In a series of posts, I'm sharing my plainer-English paraphrase of a very important article in thyroid science. My hope is that the public, doctors, and educated thyroid patients can better understand and appreciate its insights. This article by Dr. Rudolf Hoermann and colleagues Midgley, Larisch, and Dietrich explains the complex interrelationships between TSH, T4 … Continue reading Relational stability among thyroid hormones and TSH, part 1
Discordance in thyroid symptoms reported by patients and their doctors
There's no surprise that patients and doctors would disagree about the incidence rate of hypothyroid symptoms in a given patient. "We have an average of 7.2 symptoms per patient" says the cohort of 262 patients. "No, you have an average of 4.0 symptoms per patient," says the cohort of 100 doctors about those 262 patients. … Continue reading Discordance in thyroid symptoms reported by patients and their doctors