How to calculate LT3 vs. LT4 substitution: History had it right

During therapy for hypothyroidism, dose adjustments may include changing thyroid hormone pharmaceuticals or combining them in a certain ratio. To prevent overdose or underdose at the new total dosage, a physician will need to estimate the substitution, and later adjust the dose to the individual's response. The initial calculation needs to be physiologically accurate. Is … Continue reading How to calculate LT3 vs. LT4 substitution: History had it right

Thyroid therapies: What my life is like in the T3-monotherapy wheelchair

Here, I'll use my own personal example to discuss a few dimensions of T3 monotherapy, which I envision as a "wheelchair." I'm drawing on the fictional analogy I developed in an earlier post, where I imagined thyroid disease like crippling foot disease. The therapy of 100% T4 can be seen like a walking stick or … Continue reading Thyroid therapies: What my life is like in the T3-monotherapy wheelchair

Several fallacies in the TSH-T4 paradigm of thyroid therapy

When you are steeped in a medical paradigm, its fallacies can be as comfortable and taken for granted as an old pair of sneakers. In this post, I'll take apart several thyroid therapy fallacies, starting with the fallacy "description is not prescription." I will investigate many of the ways in which patients on T4 monotherapy … Continue reading Several fallacies in the TSH-T4 paradigm of thyroid therapy

In Winter, everyone gains T3 except thyroidless patients on LT4 therapy

In this article I examine the research results depicted in the graph above. Gullo and team's 2017 article reported research on 11,806 healthy controls and 3,934 thyroidless people treated with L-T4 monotherapy in Sicily, Italy. They discovered that the thyroid-disabled people lost a "significant" amount of Free T4 and Free T3 hormone in winter, on … Continue reading In Winter, everyone gains T3 except thyroidless patients on LT4 therapy

Analyze thyroid lab results using SPINA-Thyr

This post walks through the process of using the SPINA-Thyr to interpret thyroid lab test results. OVERVIEW SPINA-Thyr is a free diagnostic application developed by research endocrinologists who use it in peer-reviewed medical research. SPINA-Thyr has been in development since the late 1990s under the leadership of Dr. Johannes Dietrich, Specialist in internal medicine, endocrinology and … Continue reading Analyze thyroid lab results using SPINA-Thyr